Endogenous Creatinine Clearance as a Clinical Measure of Glomerular Filtration Rate
نویسندگان
چکیده
منابع مشابه
Endogenous creatinine clearance as a clinical measure of glomerular filtration rate.
Endogenous creatinine clearance was assessed by inulin in 91 simultaneous studies in 41 patients and proved an accurate measurement of glomerular filtration rate. For filtration rates <20 ml/min the creatinine clearance may slightly overestimate the glomerular filtration rate. Successive determinations of filtration rate by either method may vary by 20% even though the methods agree with each o...
متن کاملValidity of the endogenous creatinine clearance as a measure of glomerular filtration rate in the diseased human kidney.
Twenty-five years ago Rehberg proposed the exogenous creatinine clearance for the measurement of glomerular filtration rate (1). In the dog and rabbit, this clearance provides a simple and accurate method of determining the filtration rate, coinciding with the inulin and ferrocyanide clearances (2, 3). Subsequently, Shannon (4) and Miller and Winkler (5) found in man that the exogenous creatini...
متن کاملThe accuracy of creatinine clearance with and without urine collection as a measure of glomerular filtration rate.
Conventional creatinine clearances involving urine collections over 2, 4 and 24 hours and creatinine clearance predicted from plasma creatinine concentrations without urine collection were compared to glomerular filtration rate (GFR) estimated by 99mTc DTPA clearance in 171 patients with a wide range of GFR. All creatinine clearance methods involving urine collection had standard errors of the ...
متن کاملSerum Creatinine, Urea Nitrogen And Endogenous Creatinine Clearance Based Glomerular Filtration Rate In Camels To Evaluate Renal Functions
To evaluate renal functions in camel, the study on profiles like Serum Creatinine (SC), Serum urea nitrogen (SUN), SUN/SC ratio was undertaken in institute’s herd of camels (n=250) (Camelus dromedarius) of all age groups, both sexes and three breeds and in addition Glomerular Filtration rate (GFR) of 18 male camels of 3 breeds (n=6 each) with 6 individual replicates (Total 108 observations) wer...
متن کاملCimetidine Improves the Accuracy of Creatinine Clearance as an Indicator for Glomerular Filtration Rate
BACKGROUND Although endogenous creatinine clearance is often used as an indicator for the glomerular filtration rate (GFR), it may result in an overestimation due to its tubular secretion. Since cimetidine is known to inhibit tubular secretion of creatinine, it may improve the accuracy of the creatinine clearance in measuring GFR. METHODS Creatinine clearance (Ccr) was compared with iothalama...
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ژورنال
عنوان ژورنال: BMJ
سال: 1971
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.4.5779.84